Alzheimer’s disease Generally, the disease is thought to happen from within – but for the first time, researchers have identified cases that were triggered by a specific medical treatment.
The most common form of dementia, Alzheimer’s, is caused by the buildup of amyloid proteins in the brain. Risk factors include age, family history and health problems Lifestyle behavior and certain medical conditions.
According to a UCL press release, researchers at University College London (UCL) have linked growth hormone treatments to the development of Alzheimer’s disease in a study published in Nature Medicine.
NEW ALZHEIMER’S TREATMENT ACCELERATES PLAQUE REMOVAL FROM THE BRAIN IN CLINICAL TRIALS
Researchers studied patients who received a type of human growth hormone derived from the pituitary glands of deceased people (c-hGH).
The researchers found that c-hGH leads to greater amounts of amyloid beta protein in the brain.
Of the eight people studied who were treated with c-hGH as children, five developed symptoms of dementia and had already been diagnosed with Alzheimer’s disease or met the disease criteria.
All were between 38 and 55 years old when they experienced symptoms of cognitive decline, the study said. Genetic testing confirmed that the early disease was not inherited.
ALZHEIMER’S PATIENTS WERE DIVIDED INTO FIVE SUBGROUPS, POTENTIALLY ALLOWING “PERSONALIZED MEDICINE,” STUDY DISCOVERS
“We found that it is possible that amyloid beta pathology is transmitted and contributes to the development of Alzheimer’s disease,” said lead author Dr. Gargi Banerjee, researcher at the UCL Institute of Prion Diseases, in the press release.
“This transmission occurred after treatment with a now obsolete form of growth hormoneAnd…